American Cruise Lines
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Recommended Sailings

Our Featured Deal

  • Was $5,635 – Save up to 18%
    American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • August 2025
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $4,635
    $662pernight
    suite from
    $7,290
    $1,041pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $4,125
    $589pernight
    4.1 rating out of 5  (4 reviews)

American Cruise Lines

  • Was $5,125 – Save up to 20%
    American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Houmas House Plantation, Louisiana
    • Baton Rouge, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • November 2024
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $4,735
    $676pernight
    suite from
    $7,365
    $1,052pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $4,125
    $589pernight
    4.1 rating out of 5  (4 reviews)
  • Was $6,405 – Save up to 16%
    American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • October 2024
    • April 2025
    • May 2025
    interior from
    Not Available
    oceanview from
    $4,585
    $655pernight
    balcony from
    $5,405
    $772pernight
    suite from
    $6,935
    $991pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $4,585
    $655pernight
    4.9 rating out of 5  (7 reviews)
  • American Pride
    4.4 rating out of 5  (7 reviews)

    7 Night Columbia & Snake Rivers

    American Pride

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • October 2024
    interior from
    Not Available
    oceanview from
    $4,825
    $689pernight
    balcony from
    $5,515
    $788pernight
    suite from
    $8,730
    $1,247pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $4,825
    $689pernight
    4.4 rating out of 5  (7 reviews)
  • Was $6,075 – Save up to 16%
    American Melody
    5 rating out of 5  (8 reviews)

    7 Night Music Cities

    American Melody

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • November 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
    • Chase Visa Marriott Bonvoy card members: Extra 2 Points per dollar
    • Exclusive: Earn 3 Marriott Bonvoy Points per dollar
    • Complimentary Dining, Cocktail Parties and More
    • Ask about reduced roundtrip airfare
     
    balcony from
    $5,075
    $725pernight
    5 rating out of 5  (8 reviews)
  • Was $6,075 – Save up to 16%
    American Serenade

    7 Night Tennessee Rivers

    American Serenade

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • October 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
     
    balcony from
    $5,075
    $725pernight
  • Was $6,075 – Save up to 16%
    American Symphony
    4.2 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Houmas House Plantation, Louisiana
    • Baton Rouge, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • November 2024
    • December 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
    • Chase Visa Marriott Bonvoy card members: Extra 2 Points per dollar
    • Exclusive: Earn 3 Marriott Bonvoy Points per dollar
    • Complimentary Dining, Cocktail Parties and More
    • Ask about reduced roundtrip airfare
     
    balcony from
    $5,075
    $725pernight
    4.2 rating out of 5  (4 reviews)
  • Was $6,390 – Save up to 16%
    American Melody
    5 rating out of 5  (8 reviews)

    7 Night Lower Mississippi River

    American Melody

    Departing from: Memphis, Tennessee
    Ports of Call:
    • River Cruising
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • November 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,390
    $770pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
     
    balcony from
    $5,390
    $770pernight
    5 rating out of 5  (8 reviews)
  • Was $6,075 – Save up to 16%
    American Symphony
    4.2 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: Memphis, Tennessee
    Ports of Call:
    • River Cruising
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • Baton Rouge, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • October 2024
    • December 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
     
    balcony from
    $5,075
    $725pernight
    4.2 rating out of 5  (4 reviews)
  • Was $6,990 – Save up to 14%
    American Harmony
    5 rating out of 5  (6 reviews)

    7 Night Columbia & Snake Rivers

    American Harmony

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • May 2025
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,990
    $856pernight
    suite from
    $8,355
    $1,194pernight
    All the Cruise Line Offers & More:
     
    balcony from
    $5,990
    $856pernight
    5 rating out of 5  (6 reviews)
  • Was $8,245 – Save up to 12%
    American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Southeast Alaska

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Petersburg, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Wrangell, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    interior from
    Not Available
    oceanview from
    $6,150
    $879pernight
    balcony from
    $7,245
    $1,035pernight
    suite from
    $9,300
    $1,329pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $6,150
    $879pernight
    4.9 rating out of 5  (7 reviews)
  • Was $11,325 – Save up to 9%
    American Constellation
    4.9 rating out of 5  (7 reviews)

    10 Night Alaskan Explorer

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Cruise Inside Passage, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Sitka, Alaska
    • Wrangell, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Petersburg, Alaska
    • Cruise Inside Passage, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • June 2025
    • July 2025
    • August 2025
    interior from
    Not Available
    oceanview from
    $8,760
    $876pernight
    balcony from
    $10,325
    $1,033pernight
    suite from
    $13,180
    $1,318pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $8,760
    $876pernight
    4.9 rating out of 5  (7 reviews)
  • Was $11,385 – Save up to 9%
    American Constellation
    4.9 rating out of 5  (7 reviews)

    14 Night Alaska Inside Passage

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise Queen Charlotte Sound, British Columbia
    • Cruise Inside Passage, Alaska
    • Ketchikan, Alaska
    • Wrangell, Alaska
    • Petersburg, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    • Cruise Glacier Bay National Park
    • Haines, Alaska
    • Skagway, Alaska
    • Juneau, Alaska
    Sailing Dates:
    • May 2025
    interior from
    Not Available
    oceanview from
    $10,385
    $742pernight
    balcony from
    $12,240
    $874pernight
    suite from
    $15,570
    $1,112pernight
    All the Cruise Line Offers & More:
     
    riverview from
    $10,385
    $742pernight
    4.9 rating out of 5  (7 reviews)

See the U.S. Like Never Before Aboard American Cruise Lines

Explore the Sweet Land of Liberty Anew with River and Ocean Cruises Visiting 28 States

Set sail on the adventure of a lifetime aboard a small cruise ship or riverboat with ample amenities and top-notch service delivered by an all-American crew. A relaxed, casual atmosphere combined with an unparalleled attention to detail will make you feel right at home from the beginning to the end of your journey.

New England itineraries take you to charming seaside towns and islands, cruising the coast from Newport, Rhode Island up to Bar Harbor, Maine. Dive into the area's rich maritime history and taste some of the nation's best seafood along the way.

Across the country to the West Coast, you'll find American Cruise Lines river and ocean sailings to take you through the Pacific Northwest and Alaska. Set out on the very same trail that Lewis and Clark once traversed, see pods of orcas swimming in the Puget Sound, or sample delicious wines in wine country. Each itinerary offers so much to explore.

Sailing the Mississippi is a unique adventure all its own. With river cruises spanning St. Louis, Missouri to St. Paul, Minnesota and Memphis, Tennessee to New Orleans, Louisiana, there's so much to do and see. Visit old plantations and Civil War battlefields, tour the hometown of Mark Twain, and indulge in blues and BBQ.

Experience southern hospitality at its finest aboard Southeast cruises navigating the Intracoastal Waterway and Chesapeake Bay. Historic landmarks and local treasures abound from the great rivers of Florida to the Golden Isles and beyond.

With exceptional cuisine, daily entertainment, and complimentary experiences, traveling aboard an American Cruise Lines world-class ship is a remarkable experience you'll never forget. Book now to begin your next adventure of the United States.

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